According to health experts, PSA (Prostate-specific antigen) is considered to be a substance that is created by cells within the prostate gland (of both cancer cells and normal cells). PSA is found mainly in semen. But a god percentage also has been discovered in blood.
Frequently used tests for screening prostate cancer
There are two tests that are used to screen prostate cancer. They are as follows:
- DRE (Digital Rectal Exam): The nurse or physician inserts lubricated, gloved finger into rectum for estimating the prostate size as well as to feel any abnormality or lump present.
- PSA (Prostate particular antigen) test: PSA level are measures in blood. A substance created by prostate is the PSA. The PSA levels in blood could be higher among men suffering from prostate cancer. PSA level is likely to rise in various other conditions which might affect prostate.
With the establishment of prostate cancer, PSA level is found to spike above 4. But a level below four does not mean that the person has not been affected by cancer. Around 15% of mean having PSA below 4 are likely to have developed prostate cancer that can be found with biopsy.
Men with PSA level of 4-10 have around 1-4 chances of developing prostate cancer. In case, PSA is found to be over 10, then the risk of developing prostate cancer can be more than 50%.
In case, PSA level is found to be quite high, then the physician at the best Prostate Cancer hospital in India is sure to recommend waiting for a while and to duplicate the test. Otherwise, he may suggest getting prostate biopsy for identifying if the person has developed cancer or not. When it comes to detecting prostate cancer, the biopsy PSA cutoff point conducted by the physicians is not the same. Few may encourage biopsy only if there are 4 and above PSA level. The others might recommend starting at much lower level like 2.5 or 3. There are other factors that might impact the choice made like family history, age and race.
Some elements which might impact levels of PSA
PSA levels may be raised due to various aspects that might take place besides prostate cancer.
- Old age: Usually, PSA levels go up slowly with age, even if no prostate problem is noticed.
- Bigger prostate: There are few conditions like BPH (benign prostatic hyperplasia), a non-cancerous prostate augmentation which affects men as they age and raise PSA levels.
- Ejaculation: PSA levels may go up for some time and reduce again. Hence, physicians recommend men to avoid ejaculation for about a day or even more before the test.
- Prostatitis: It is a term that best describes inflammation or infection of prostate gland. It can raise levels of PSA.
- Certain medications: Intake of male hormonal agents such as testosterone or any other medicines which might increase testosterone levels could cause PSA levels to increase significantly.
Checking at the best hospital for prostate cancer treatment in India will help the patient to get the right treatment.